Fixed dose drug combination formulations

596064 A stable pharmaceutical formulation in the form of a capsule comprising: a) a tablet comprising cholesterol lowering agent (for example simvastatin); b) a tablet comprising aspirin; c) i. a tablet comprising an inhibitor of the renin-angiotensin system (for example lisinopril); and ii. a beta-adrenergic receptor blocking agent or a diuretic (for example atenolol or hydrochiorothiazide); wherein any one or more of the tablets is coated; and wherein any individual impurity related to an active agent is present in amounts less than about 5 percent of the label content of the active agent, and the total impurities related to active agents are present in amounts less than about 7 percent of the label content of the active agents.