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Provided is an ex-vivo method for assessing the efficacy of a treatment in a patient receiving an immunogenic composition, wherein the method comprises: measuring levels of interferon gamma in a biological sample from the patient after the patient has received the immunogenic composition; wherein le...

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Bibliographische Detailangaben
Hauptverfasser:	BERANGERE, MARIE-BASTIEN, ACRES, BRUCE
Format:	Patent
Sprache:	eng
Schlagworte:	INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING PHYSICS TESTING
Online-Zugang:	Volltext bestellen
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Beschreibung
Zusammenfassung:	Provided is an ex-vivo method for assessing the efficacy of a treatment in a patient receiving an immunogenic composition, wherein the method comprises: measuring levels of interferon gamma in a biological sample from the patient after the patient has received the immunogenic composition; wherein levels of interferon gamma above about 4 pg/ml indicate a successful clinical outcome for the treatment and wherein said immunogenic composition contains at least one recombinant viral vector expressing in vivo all or part of MUC antigen, provided that the recombinant viral vector does not express interferon gamma.