YEAST EXPRESSING CELLULASES FOR SIMULTANEOUS SACCHARIFICATION AND FERMENTATION USING CELLULOSE

A thermotolerant yeast host cell comprising: (a) at least one heterologous polynucleotide comprising a nucleic acid which encodes an endoglucanase; (b) at least one heterologous polynucleotide comprising a nucleic acid which encodes a ß-glucosidase; (c) at least one heterologous polynucleotide compr...

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Hauptverfasser: SIIKA-AHO, MATTI, MCBRIDE, JOHN, HAU, HEIDI HANSON, STONEHOUSE, EMILY A, VAN ZYL, EMILE, MELLON, MARK, XU, HAOWEN, DEN HAAN, RIAAN, SHIKHARE, INDRANEEL, WILLES, DEIDRE, ROSE, SHAUNITA, GILBERT, ALAN, RAJGARHIA, VINEET, KEATING, JEFFREY D, PENTTILA, MERJA, MURPHY, DAN, RICE, CHARLES, LAGRANGE, DANIE, UUSITALO, JAANA, FROEHLICH, ALAN, VILLARI, JEFF, GHANDI, CHHAYAL, BREVNOVA, ELENA, FLATT, JIM, DELEAULT, KRISTEN, THORNGREN, NAOMI, ILMEN, MARJA, WARNER, ANNE K
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Sprache:eng
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Zusammenfassung:A thermotolerant yeast host cell comprising: (a) at least one heterologous polynucleotide comprising a nucleic acid which encodes an endoglucanase; (b) at least one heterologous polynucleotide comprising a nucleic acid which encodes a ß-glucosidase; (c) at least one heterologous polynucleotide comprising a nucleic acid which encodes a cellobiohydrolase I; and (d) at least one heterologous polynucleotide comprising a nucleic acid which encodes a cellobiohydrolase II; wherein the host cell is capable of producing ethanol when grown using cellulose as a carbon source.