New Antitumoral Compounds comprising modified kahalalide F

New Antitumoral Compounds comprising modified kahalalide F

Disclosed is a compound of formula (1) based on the structure of kahalalide F, wherein the kahalalide F structure is modified at the 5-Mehex 14 position with an octanoic acid group. Also disclosed is the use of the compound of formula (1) for treating cancer.

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Bibliographische Detailangaben
Hauptverfasser: FERNANDEZ DONIS, ARIADNA, EXPOSITO, MIRIAM ROYO, COLOMER, SONIA VARON, MACIA, ANGEL LOPEZ, CANTADOR, CAROLINA GRACIA, SOLLOSO, ANDRES FRANCESCH, RODRIGUEZ, PILAR LOPEZ, CUEVAS, CARMEN, JIMENEZ, JOSE CARLOS, LLEDO, ERNEST GIRALT, PALOMERA, FERNANDO ALBERICIO
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:Disclosed is a compound of formula (1) based on the structure of kahalalide F, wherein the kahalalide F structure is modified at the 5-Mehex 14 position with an octanoic acid group. Also disclosed is the use of the compound of formula (1) for treating cancer.