Warming and nonirritating lubricant antifungal gel compositions

Anhydrous anti-fungal gel compositions comprising from about 80 wt.% to about 98 wt.% of at least two polyhydric alcohols, a gelling agent, an antifungal imidazole and an organic acid as a pH adjustment agent are disclosed, wherein said antifungal imidazole compound may selected from the group consi...

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Hauptverfasser: LAMB, CHRISTOPHER SCOTT, LONARDO, EMILIA CASILIO, AHMAD, NAWAZ
Format: Patent
Sprache:eng
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Zusammenfassung:Anhydrous anti-fungal gel compositions comprising from about 80 wt.% to about 98 wt.% of at least two polyhydric alcohols, a gelling agent, an antifungal imidazole and an organic acid as a pH adjustment agent are disclosed, wherein said antifungal imidazole compound may selected from the group consisting of econazole, terconazole, saperconazole, itraconazole, butaconazole, clotrimazole, tioconazole, fluconazole and ketoconazole, vericonazole, fenticonazole, sertaconazole, posaconazole, bifonazole, oxiconazole, sulconazole, elubiol, verconazole, isoconazole, flutrimazole, tioconazole and their pharmaceutically acceptable salts; wherein said polyhydric alcohol may be selected from the group consisting of: glycerin, alkylene glycol, polyethylene glycol and a mixture thereof, and wherein said organic acid may be an alphahydroxy acid such as lactic acid. (62) Divided Out of 575859