Inhibitors of the chemokine receptor CxCR3

Disclosed is a 3-(amido or sulfamido)-4-(4-substituted-azinyl)benzamide or benzsulfonamide compound of formula (I) where Q and Y are CO or SO2, X is halo, m is 1-3, R5 is a monovalent group as described or is a spiro ring as described, and wherein the other substituents are as described in the speci...

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1. Verfasser: THORPE, DAVID S
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description Disclosed is a 3-(amido or sulfamido)-4-(4-substituted-azinyl)benzamide or benzsulfonamide compound of formula (I) where Q and Y are CO or SO2, X is halo, m is 1-3, R5 is a monovalent group as described or is a spiro ring as described, and wherein the other substituents are as described in the specification. Also disclosed is the use of the compound to treat CxCR3 chemokine receptor mediated diseases or conditions.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Inhibitors of the chemokine receptor CxCR3
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