Inhibitors of the chemokine receptor CxCR3

Disclosed is a 3-(amido or sulfamido)-4-(4-substituted-azinyl)benzamide or benzsulfonamide compound of formula (I) where Q and Y are CO or SO2, X is halo, m is 1-3, R5 is a monovalent group as described or is a spiro ring as described, and wherein the other substituents are as described in the speci...

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Bibliographische Detailangaben
1. Verfasser:	THORPE, DAVID S
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Disclosed is a 3-(amido or sulfamido)-4-(4-substituted-azinyl)benzamide or benzsulfonamide compound of formula (I) where Q and Y are CO or SO2, X is halo, m is 1-3, R5 is a monovalent group as described or is a spiro ring as described, and wherein the other substituents are as described in the specification. Also disclosed is the use of the compound to treat CxCR3 chemokine receptor mediated diseases or conditions.