THIENO-AND FURO-PYRIMIDINE MODULATORS OF THE HISTAMINE H4 RECEPTOR

Thieno- and furo-pyrimidine compounds of formula (I) are disclosed, which are useful as H4 receptor modulators. These compounds may be used in pharmaceutical compositions and methods for the modulation of histamine H4 receptor activity and for the treatment of disease states, disorders, and conditio...

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Hauptverfasser: WIENER, DANIELLE, K, EDWARDS, JAMES P, VENABLE, JENNIFER, SMITH, DEBORAH, M
Format: Patent
Sprache:eng
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Zusammenfassung:Thieno- and furo-pyrimidine compounds of formula (I) are disclosed, which are useful as H4 receptor modulators. These compounds may be used in pharmaceutical compositions and methods for the modulation of histamine H4 receptor activity and for the treatment of disease states, disorders, and conditions mediated by H4 receptor activity, such as inflammation.