INDUSTRIAL METHOD FOR THE SYNTHESIS OF 17-ACETOXY-11-BETA-[4-(DIMETHYLAMINO)-PHENYL]-21-METHOXY-19-NORPREGNA-4,9-DIEN-3,20-DIONE AND THE KEY INTERMEDIATES OF THE PROCESS
Disclosed is a process for the synthesis of 17-acetoxy-11-beta-[4-(dimethylamino)-phenyl]-21-methoxy-19-norpregna-4,9-dien-3,20-dione of formula (I) from 3,3-[1,2-etandiyl-bis(oxy)]-oestr-5(10),9(l l)-dien-17-one of formula (II).
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creator | TERDY, LASZLO SANTA, CSABA TUBA, ZOLTAN CSORGEI, JANOS MOLNAR, CSABA MAHO, SANDOR HORVATH, ZOLTAN BALOGH, GABOR VISKY, GYORGY BODI, JOZSEF SZELES, JANOS ARANYI, ANTAL |
description | Disclosed is a process for the synthesis of 17-acetoxy-11-beta-[4-(dimethylamino)-phenyl]-21-methoxy-19-norpregna-4,9-dien-3,20-dione of formula (I) from 3,3-[1,2-etandiyl-bis(oxy)]-oestr-5(10),9(l l)-dien-17-one of formula (II). |
format | Patent |
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title | INDUSTRIAL METHOD FOR THE SYNTHESIS OF 17-ACETOXY-11-BETA-[4-(DIMETHYLAMINO)-PHENYL]-21-METHOXY-19-NORPREGNA-4,9-DIEN-3,20-DIONE AND THE KEY INTERMEDIATES OF THE PROCESS |
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