INDUSTRIAL METHOD FOR THE SYNTHESIS OF 17-ACETOXY-11-BETA-[4-(DIMETHYLAMINO)-PHENYL]-21-METHOXY-19-NORPREGNA-4,9-DIEN-3,20-DIONE AND THE KEY INTERMEDIATES OF THE PROCESS

INDUSTRIAL METHOD FOR THE SYNTHESIS OF 17-ACETOXY-11-BETA-[4-(DIMETHYLAMINO)-PHENYL]-21-METHOXY-19-NORPREGNA-4,9-DIEN-3,20-DIONE AND THE KEY INTERMEDIATES OF THE PROCESS

Disclosed is a process for the synthesis of 17-acetoxy-11-beta-[4-(dimethylamino)-phenyl]-21-methoxy-19-norpregna-4,9-dien-3,20-dione of formula (I) from 3,3-[1,2-etandiyl-bis(oxy)]-oestr-5(10),9(l l)-dien-17-one of formula (II).

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Bibliographische Detailangaben
Hauptverfasser: TERDY, LASZLO, SANTA, CSABA, TUBA, ZOLTAN, CSORGEI, JANOS, MOLNAR, CSABA, MAHO, SANDOR, HORVATH, ZOLTAN, BALOGH, GABOR, VISKY, GYORGY, BODI, JOZSEF, SZELES, JANOS, ARANYI, ANTAL
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
STEROIDS
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Zusammenfassung:Disclosed is a process for the synthesis of 17-acetoxy-11-beta-[4-(dimethylamino)-phenyl]-21-methoxy-19-norpregna-4,9-dien-3,20-dione of formula (I) from 3,3-[1,2-etandiyl-bis(oxy)]-oestr-5(10),9(l l)-dien-17-one of formula (II).