MEDICINAL DELIVERY SYSTEM AND RELATED METHODS COMPRISING A NICOTINE COATED ON A SALIVA-SOLUBLE POWDER SUCH AS SORBITOL

MEDICINAL DELIVERY SYSTEM AND RELATED METHODS COMPRISING A NICOTINE COATED ON A SALIVA-SOLUBLE POWDER SUCH AS SORBITOL

Disclosed is a method of making a medicinal delivery system for oral delivery of a nicotine compound which satiates nicotine craving for an individual in need of nicotine-craving relief, comprising: providing a paste comprising a solvent-treated nicotine compound that has been at least partially dis...

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1. Verfasser: CHAU, TOMMY L
Format: Patent
Sprache:eng
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HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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creator CHAU, TOMMY L
description Disclosed is a method of making a medicinal delivery system for oral delivery of a nicotine compound which satiates nicotine craving for an individual in need of nicotine-craving relief, comprising: providing a paste comprising a solvent-treated nicotine compound that has been at least partially dissolved in a solvent of a bulk sweetener solution to make the nicotine compound more readily dissolvable during ingestion or mastication to promote a high initial nicotine release rate; coating a saliva-soluble bulk sweetener powder with the paste to establish a coated powder premix; and subsequent to establishing the coated powder premix, substantially homogenously distributing the coated powder premix in an edible carrier base selected from the group consisting of a chewing gum base and a lozenge base and combining the edible carrier base and the coated powder premix with a buffer to establish a medicinal delivery system.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title MEDICINAL DELIVERY SYSTEM AND RELATED METHODS COMPRISING A NICOTINE COATED ON A SALIVA-SOLUBLE POWDER SUCH AS SORBITOL
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