The use of benzamide or pyridinamide derivatives as antibacterial agents

Disclosed is the use of a primary benzamide or pyridylamide of formula (I) or a salt, hydrate, or solvate thereof, in the manufacture of a medicament for use in treating bacterial infection: wherein R represents hydrogen W is =C(R1)- or =N-; R1 is hydrogen and R2 is hydrogen, methyl, or fluorine; or R1 and R2 taken together are methylene, ethylene, -O-, or, in either orientation, -O-methylene or -O-ethylene; R3 is a radical of formula -(Alk1)m-(Z)p-(Alk2)kQ wherein m, p and n are independently 0 or 1, Z is -O-, -S-, -S(O)-, -S(O2)-, -NH-, -N(CH3)-, -N(CH2CH3)-,-C(=O)-, -O-(C=O)-, -C(=O)-O-, or a divalent monocyclic carbocyclic or heterocyclic radical; or a divalent bicyclic heterocyclic; Alk 1 and Alk2 are alkylene, alkenylene, or alkynylene radicals and Q is hydrogen, halogen, nitrile, or a monocyclic carbocyclic or heterocyclic radical; or a bicyclic heterocyclic radical. Also disclosed are pyridyl and benzamide compounds.