Complexes of protein crystals and ionic polymers comprising human growth hormone and protamine

Disclosed is the use of a complex in the preparation of a medicament for the treatment of a disease state in a mammal other than a disorder associated with human growth hormone deficiency in a human, wherein said complex comprises a human growth hormone (hGH) crystal and protamine, wherein the prota...

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Bibliographische Detailangaben
Hauptverfasser: KHALAH, NAZER, GOVARDHAN, CHANDRIKA
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:Disclosed is the use of a complex in the preparation of a medicament for the treatment of a disease state in a mammal other than a disorder associated with human growth hormone deficiency in a human, wherein said complex comprises a human growth hormone (hGH) crystal and protamine, wherein the protamine is co-crystallised with the hGH or is complexed with the hGH crystal.