Changing Th1/Th2 balance in split influenza vaccines with adjuvants

Disclosed is an immunogenic composition comprising a split influenza virus antigen when prepared from a virus grown in cell culture, and a Th1 adjuvant in the form of an oil-in-water emulsion comprising oil droplets having a submicron diameter, wherein said emulsion comprises squalene, and wherein s...

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Hauptverfasser:	DEL GUIDICE, GUISEPPE, RAPPUOLI, RINO, O'HAGAN, DEREK
Format:	Patent
Sprache:	eng
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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