N-Phenyl-2-pyrimidine-amine derivatives and process for the preparation thereof

N-Phenyl-2-pyrimidine-amine derivatives and process for the preparation thereof

Disclosed are N-phenyl-2-pyrimidine-amine derivatives of formula (1) wherein one of R4 or R5 must be a radical of formula (2). A process for preparing the said compounds is also disclosed. Also disclosed is the use of the said compound in a pharmaceutical composition for the manufacture of a medicam...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: LEE, SUN-AHE, KIM, DONG-YEON, KIM, HONG-YOUB, KIM, YONG-SEOK, CHO, DAE-JIN, LEE, GONG-YEAL, WOO, SEOK-HUN, HAN, BYOUNGOL
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:Disclosed are N-phenyl-2-pyrimidine-amine derivatives of formula (1) wherein one of R4 or R5 must be a radical of formula (2). A process for preparing the said compounds is also disclosed. Also disclosed is the use of the said compound in a pharmaceutical composition for the manufacture of a medicament for the treatment of cancer.