P-cadherin antibodies

Provided is an isolated antibody or antigen-binding portion thereof that binds to P-cadherin and comprises a VH domain and a VL domain, wherein the VH domain comprises: a) a VH CDR1, b) a VH CDR2, and c) a VH CDR3, and wherein the VL domain comprises: d) a VL CDR1, e) a VL CDR2 and f) a VL CDR3, all...

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Hauptverfasser: BOURNER, MAUREEN JERI, HEAD, RICHARD DAVID, MINTER, RALPH RAYMOND, BAUER, CHRISTOPHER TODD, JOY, WILLIAM DEAN, BOYLE, MELANIE, MOFFAT, MARK ALLEN, GRIGGS, DAVID WILLIAM, MAZZARELLA, RICHARD ALLEN, THIELE, BARRETT RICHARD, VANARSDALE, TODD LEE, CASPERSON, GERALD FRIES
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creator BOURNER, MAUREEN JERI
HEAD, RICHARD DAVID
MINTER, RALPH RAYMOND
BAUER, CHRISTOPHER TODD
JOY, WILLIAM DEAN
BOYLE, MELANIE
MOFFAT, MARK ALLEN
GRIGGS, DAVID WILLIAM
MAZZARELLA, RICHARD ALLEN
THIELE, BARRETT RICHARD
VANARSDALE, TODD LEE
CASPERSON, GERALD FRIES
description Provided is an isolated antibody or antigen-binding portion thereof that binds to P-cadherin and comprises a VH domain and a VL domain, wherein the VH domain comprises: a) a VH CDR1, b) a VH CDR2, and c) a VH CDR3, and wherein the VL domain comprises: d) a VL CDR1, e) a VL CDR2 and f) a VL CDR3, all with specified sequences or variants differing only by 1 or 2 conservative amino acid substitutions. Further provided are corresponding nucleic acid molecules encoding said antibodies, with specified sequences.
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subjects CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title P-cadherin antibodies
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