The use of carbazole derivatives for the treatment or prophylaxis of diseases or conditions caused by ischaemic damage to tissues of peripheral organs

Disclosed is the use of carbazole derivatives of general formula (I), in which: X represents >CR1R2 or, when R6 does not represent a hydrogen atom, X can also represent >SO2; Y is >CR1R2; Z is >C=O, >CH2 or a direct bond; R1 is hydrogen atom and R2 is hydrogen, a carboxy group or a hydroxy group; or R1 and R2 together represent an oxo group, an ethylenedioxy group or a hydroxyimino group; R3 is hydrogen or alkyl; R4 represents two hydrogen atoms, or an oxo or hydroxyimino group; R5 is hydrogen, alkyl or halogen; R6 is hydrogen, alkoxy, or a carboxy group; R7 and R8 are independently represented by hydrogen, alkyl or halogen; and pharmaceutically acceptable salts and esters thereof for the manufacture of a medicament for the treatment or prophylaxis of diseases or conditions caused by ischaemic damage to tissues of peripheral organs. Of particular importance are the compounds 7,8-dimethyl-2,3,4,9-tetrahydro-1H-carbazol-3-ol, 5,8-dimethyl-2,3,4,9-tetrahydro-1H-carbazol-3-ol, 8-methoxy-1,3,4,5-tetrahydrothiopyrano[4,3-b]indole 2,2-dioxide and 5,8-dimethyl-2,3,4,9-tetrahydro-1H-carbazole-2-carboxylic acid,