DNA sequences for human angiogenesis genes

Disclosed is the use of an antisense nucleic acid molecule, DNAzyme, ribozyme or an antibody, which specifically modulates the expression of the disclosed nucleic acid sequence (SEQ ID NO: 29) in the manufacture of a medicament for treating certain disorders related to angiogenesis. The disorders ar...

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Bibliographische Detailangaben
Hauptverfasser:	HAHN, CHRISTOPHER NORMAN, GAMBLE, JENNIFER RUTH, VADAS, MATHEW ALEXANDER
Format:	Patent
Sprache:	eng
Schlagworte:	AGRICULTURE ANIMAL HUSBANDRY BEER BIOCHEMISTRY CARE OF BIRDS, FISHES, INSECTS CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE FISHING FORESTRY HUMAN NECESSITIES HUNTING HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING NEW BREEDS OF ANIMALS ORGANIC CHEMISTRY PEPTIDES PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES OF PREPARING SUCH COMPOSITIONS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS TESTING TRAPPING VINEGAR WINE
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Beschreibung
Zusammenfassung:	Disclosed is the use of an antisense nucleic acid molecule, DNAzyme, ribozyme or an antibody, which specifically modulates the expression of the disclosed nucleic acid sequence (SEQ ID NO: 29) in the manufacture of a medicament for treating certain disorders related to angiogenesis. The disorders are cancer, rheumatoid arthritis, diabetic retinopathy, psoriasis and cardiovascular disease. Further uses for SEQ ID NO: 29 are disclosed including genetically modified animals containing such and screening methods for candidate molecules.