Indane and tetralin derivatives which potentiate glutamate receptor and uses thereof in medicine

Indane and tetralin derivatives which potentiate glutamate receptor and uses thereof in medicine

Disclosed is a compound of formula (I), or a pharmaceutically acceptable salt, solvate, or prodrug thereof, wherein n is 1 or 2, p is 0, 1, or 2, and wherein the substituents are as defined in the specification. Also disclosed is a process for preparing the compound and it use in treating diseases o...

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Bibliographische Detailangaben
Hauptverfasser: THEWLIS, KEVIN MICHAEL, BRADLEY, DANIEL MARCUS, WARD, SIMON EDWARD
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:Disclosed is a compound of formula (I), or a pharmaceutically acceptable salt, solvate, or prodrug thereof, wherein n is 1 or 2, p is 0, 1, or 2, and wherein the substituents are as defined in the specification. Also disclosed is a process for preparing the compound and it use in treating diseases or conditions caused by a reduction or imbalance in glutamate receptor function, such as schizophrenia.