Genes in Group B Streptococcus (GBS), and also related organisms, the products of which are associated with the outer surface of the organism, and are useful as targets for immunotherapy

Disclosed is a peptide encoded by the nucleotide sequence of SEQ ID NO: 7, or by the amino acid sequence of SEQ ID NO: 8, obtainable from Group B streptococcus. The peptide or polynucleotide can be used in a medicament for the treatment of bacterial infections, particularly when the infection is a f...

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Bibliographische Detailangaben
Hauptverfasser:	HUGHES, MARTIN JOHN GLENTON, MOORE, JOANNE CHRISTINE, FELDMAN, ROBERT, DOBSON, RICHARD JAMES, DOUGAN, GORDON, HENWOOD, CAROLINE JOANNE, EVEREST, PAUL, WILSON, REBECCA KERRY, SANTANGELO, JOSEPH DAVID, LANE, JONATHAN DOUGLAS
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES OF PREPARING SUCH COMPOSITIONS PROCESSES USING MICROORGANISMS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	Disclosed is a peptide encoded by the nucleotide sequence of SEQ ID NO: 7, or by the amino acid sequence of SEQ ID NO: 8, obtainable from Group B streptococcus. The peptide or polynucleotide can be used in a medicament for the treatment of bacterial infections, particularly when the infection is a focal or urinary tract infection. Also described are antibodies and hosts transformed with the peptide.