Dosage form with a core tablet of active ingredient sheathed in a compressed annular body of powder or granular material, and process and tooling for producing it

A toolset for producing a solid pharmaceutical dosage form comprising a core tablet sheathed in a compressed annular body of powder or granular material, the toolset comprising: a) a columnar punch having a protrusion, and b) a punch assembly comprising an annular punch and a core rod slidably engag...

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Hauptverfasser: AQUA, OFER, FLASHNER-BARAK, MOSHE, ROSENBERGER, VERED, LERNER, E ITZHAK
Format: Patent
Sprache:eng
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Zusammenfassung:A toolset for producing a solid pharmaceutical dosage form comprising a core tablet sheathed in a compressed annular body of powder or granular material, the toolset comprising: a) a columnar punch having a protrusion, and b) a punch assembly comprising an annular punch and a core rod slidably engageable with the annulus of the annular punch, wherein the core rod is capable of movement between a retracted position and an extended position and wherein the core rod is biased in an extended position.