7-[imidazol-1-yl]-3,5-dihydroxyheptanoic acids and lactone forms

Disclosed are compounds of formula I and their lactone forms, wherein the substituents are as defined in the specification. The compounds are HMGCo-A reductase inhibitors useful in the treatment of hyperlipidemia, hypercholesterolemia, hypertriglyceridemia and atherosclerosis.

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Bibliographische Detailangaben
Hauptverfasser: BOLTON, GARY LOUIS, HOWARD, WALTER ALLEN, HUTCHINGS, RICHARD HENRY, BOYLES, DAVID CHRISTOPHER, KENNEDY, ROBERT MICHAEL, SONG, YUNTAO, TRIVEDI, BHARAT KALIDAS, BOWLES, DANIEL MERRITT, PARK, WILLIAM KEUNAN
Format: Patent
Sprache:eng
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Zusammenfassung:Disclosed are compounds of formula I and their lactone forms, wherein the substituents are as defined in the specification. The compounds are HMGCo-A reductase inhibitors useful in the treatment of hyperlipidemia, hypercholesterolemia, hypertriglyceridemia and atherosclerosis.