Liquid formulations for the prevention and treatment of mucosal diseases and disorders

Liquid formulations for the prevention and treatment of mucosal diseases and disorders

Disclosed is a liquid composition for the treatment of an oral mucocutaneous disorder, consisting essentially of 0.1w/w% to about 3.0w/w% of one or more mucoadhesives in an aqueous solution that exhibits pseudoplastic behaviour when shear is applied and has a zero-shear viscosity at 37 ± 1 degree Ce...

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Hauptverfasser: NOWOTNIK, DAVID P, JACOB, JEREMY E, BAUD, CHRISTINE M
Format: Patent
Sprache:eng
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HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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creator NOWOTNIK, DAVID P
JACOB, JEREMY E
BAUD, CHRISTINE M
description Disclosed is a liquid composition for the treatment of an oral mucocutaneous disorder, consisting essentially of 0.1w/w% to about 3.0w/w% of one or more mucoadhesives in an aqueous solution that exhibits pseudoplastic behaviour when shear is applied and has a zero-shear viscosity at 37 ± 1 degree Celsius of 5,000 to 20,000 centipoise wherein the mucoadhesive consists of one or more linear or cross-linked polymer(s) selected from the group consisting of polyacrylic acid, carbomer, carboxymethylcellulose, hydroxyalkylcellulose, dextran sulfate, dermatan sulfate, chitosan, and a water-soluble vinyl polymer.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title Liquid formulations for the prevention and treatment of mucosal diseases and disorders
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