Substituted azole derivatives, compositions, and methods of use

Substituted azole derivatives, compositions, and methods of use

The disclosure relates to azole derivatives of formula (I), methods of their preparation, pharmaceutical compositions comprising the compounds of formula (I), and their use in treating human or animal disorders. These compounds can be useful as inhibitors of protein tyrosine phosphatases and thus ca...

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Bibliographische Detailangaben
Hauptverfasser: ANDREWS, ROBERT C, MJALLI, ADNAN M M, ARIMILLI, MURTY N, SUBRAMANIAN, GOVINDAN, YARRAGUNTA, RAVINDRA R, QUADA, JAMES C, XIE, RONGYUAN, POLISETTI, DHARMA R
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The disclosure relates to azole derivatives of formula (I), methods of their preparation, pharmaceutical compositions comprising the compounds of formula (I), and their use in treating human or animal disorders. These compounds can be useful as inhibitors of protein tyrosine phosphatases and thus can be useful for the management, treatment, control, or the adjunct treatment of diseases mediated by PTPase activity. Such diseases include Type I diabetes and Type II diabetes.