Microparticles comprising somatostatin analogues

Microparticles comprising somatostatin analogues

Disclosed are microparticles comprising cyclo[{4-(NH2-C2H4-NH-CO-O-)Pro}-Phg-DTrp-Lys-Tyr(4-Bzl)-Phe] in free form, salt form or protected form, embedded in a polymer matrix, wherein the polymer matrix comprises a linear and a branched polylactide-co-glycolide. Also disclosed is the use of the micro...

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Bibliographische Detailangaben
Hauptverfasser: LAMBERT, OLIVIER, AHLHEIM, MARKUS, AUSBORN, MICHAEL, RIEMEN-SCHNITTER, MARC
Format: Patent
Sprache:eng
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:Disclosed are microparticles comprising cyclo[{4-(NH2-C2H4-NH-CO-O-)Pro}-Phg-DTrp-Lys-Tyr(4-Bzl)-Phe] in free form, salt form or protected form, embedded in a polymer matrix, wherein the polymer matrix comprises a linear and a branched polylactide-co-glycolide. Also disclosed is the use of the microparticles for treating diseases or disorders with an aetiology comprising or associated with excess GH- or IGF-1 secretion.