Use of IL-18 inhibitors for the treatment of Chron's disease

Disclosed is the use of an IL-18 inhibitor selected from IL-18 binding proteins, isoforms, muteins, fused proteins, functional derivatives, active fractions or circularly permutated derivatives thereof having essentially the same activity as an IL-18 binding protein for the manufacture of a medicame...

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Bibliographische Detailangaben
Hauptverfasser:	RUBINSTEIN, MENA, PLATER-ZYBERK, CHRISTINE, KIM, SOO-HYUN, CHVATCHKO, YOLANDE, NOVICK, DANIELA, DINARELLO, CHARLES, VAN DEVENTER, SANTER
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	Disclosed is the use of an IL-18 inhibitor selected from IL-18 binding proteins, isoforms, muteins, fused proteins, functional derivatives, active fractions or circularly permutated derivatives thereof having essentially the same activity as an IL-18 binding protein for the manufacture of a medicament for the treatment and/or prevention of Crohn's disease.