Tubulin inhibitors

Disclosed are compounds represented by Fomula (I), (II), (III) and (V), or pharmaceutically acceptable prodrugs, salts, hydrates, solvates, crystal forms or diastereomers thereof wherein the substituents are listed in the specification. These compounds can be used in the manufacture of a medicament...

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Hauptverfasser: WILKS, ANDREW FREDERICK, BURNS, CHRISTOPHER JOHN, HARTE, MICHAEL FRANCIS, FANTINO, EMMANUELLE, SIKANYIKA, HARRISON, SIMS, COLETTE GLORIA
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creator WILKS, ANDREW FREDERICK
BURNS, CHRISTOPHER JOHN
HARTE, MICHAEL FRANCIS
FANTINO, EMMANUELLE
SIKANYIKA, HARRISON
SIMS, COLETTE GLORIA
description Disclosed are compounds represented by Fomula (I), (II), (III) and (V), or pharmaceutically acceptable prodrugs, salts, hydrates, solvates, crystal forms or diastereomers thereof wherein the substituents are listed in the specification. These compounds can be used in the manufacture of a medicament for modulating microtubule polymerisation and in the treatment of associated disease states.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Tubulin inhibitors
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