Thienopyridazinone derivatives as modulators of autoimmune diseases

Thienopyridazinone derivatives as modulators of autoimmune diseases

Disclosed is a compound of formula (I), wherein R3 is a group CO-G or SO2-G and the remaining substituents are as defined in the specification. The compounds are inhibitors of T-cell proliferation and are useful in the modulation of autoimmune disease.

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Bibliographische Detailangaben
Hauptverfasser: INGALL, ANTHONY HOWARD, COOPER, MARTIN EDWARD, GUILE, SIMON DAVID, RASUL, RUKHSANA TASNEEM
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:Disclosed is a compound of formula (I), wherein R3 is a group CO-G or SO2-G and the remaining substituents are as defined in the specification. The compounds are inhibitors of T-cell proliferation and are useful in the modulation of autoimmune disease.