Diaminotriazoles useful as inhibitors of protein kinases

Diaminotriazoles useful as inhibitors of protein kinases

Disclosed is a compound of formula (II) or (II'), wherein R1 is hydrogen, R2 is a substituted phenyl or a substituted 3-7-membered saturated or partially unsaturated monocyclic ring having 0-3 heteroatoms selected from nitrogen, oxygen, or sulfur, or an 8-12-membered saturated or partially unsa...

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Hauptverfasser: DAVIES, ROBERT J, LEDEBOER, MARK, XU, JINWANG, GALULLO, VINCENT, SALITURO, FRANCESCO G, FORSTER, CORNELIA J, PIERCE, ALBERT C, GREY, RONALD, HENKEL, GREG, TIAN, SHI-KAI, BINCH, HAYLEY, NANTHAKUMAR, SUGANTHI, MESSERSMITH, DAVID, LEDFORD, BRIAN, ARNOST, MICHAEL, WANG, JIAN, JAYARAJ, ANDREW
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:Disclosed is a compound of formula (II) or (II'), wherein R1 is hydrogen, R2 is a substituted phenyl or a substituted 3-7-membered saturated or partially unsaturated monocyclic ring having 0-3 heteroatoms selected from nitrogen, oxygen, or sulfur, or an 8-12-membered saturated or partially unsaturated bicyclic ring system having 0-5 heteroatoms independently selected from nitrogen, oxygen or sulfur, and the remaining substituents are as defined in the specification. The compounds are useful as inhibitors of protein kinases.