Controlled-release of an active substance into a high fat environment

Controlled-release of an active substance into a high fat environment

Disclosed is a use of a composition comprising an active-substance-containing core and an asymmetric polymeric coating thereon, in the manufacture of a medicament for controlled-release delivery upon administration of said composition to a use environment comprising at least about 0.5 wt% of dietary...

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Hauptverfasser: OKSANEN, CYNTHIA ANN, FRIESEN, DWAYNE THOMAS, NIGHTINGALE, JAMES ALAN SCHRIVER, CHIDLAW, MARK BRIAN, HERBIG, SCOTT MAX, WEST, JAMES BLAIR
Format: Patent
Sprache:eng
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HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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creator OKSANEN, CYNTHIA ANN
FRIESEN, DWAYNE THOMAS
NIGHTINGALE, JAMES ALAN SCHRIVER
CHIDLAW, MARK BRIAN
HERBIG, SCOTT MAX
WEST, JAMES BLAIR
description Disclosed is a use of a composition comprising an active-substance-containing core and an asymmetric polymeric coating thereon, in the manufacture of a medicament for controlled-release delivery upon administration of said composition to a use environment comprising at least about 0.5 wt% of dietary fat, wherein the polymer used to form said asymmetric polymeric coating comprises cellulose acetate, cellulose acetate butyrate, cellulose acetate propionate, cellulose acetate phthalate, hydroxypropyl methyl cellulose acetate succinate, polymethacrylate, or mixtures or-blends thereof.
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subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
title Controlled-release of an active substance into a high fat environment
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