Hydroxyethylamine derivatives for the treatment of alzheimer's disease
Hydroxyethylamine compounds of formula (I) as defined in the description having Asp2 (-secretase, BACE1 or Memapsin) inhibitory activity, processes for their preparation, to compositions containing them and to their use in the treatment of diseases characterised by elevated - amyloid levels or -amyl...
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| creator | STANWAY, STEVEN JAMES VESEY, DAVID R DEMONT, EMMANUEL H WALTER, DARYL S FALLER, ANDREW REDSHAW, SALLY MACPHERSON, DAVID TIMOTHY MILNER, PETER HENRY NAYLOR, ALAN |
| description | Hydroxyethylamine compounds of formula (I) as defined in the description having Asp2 (-secretase, BACE1 or Memapsin) inhibitory activity, processes for their preparation, to compositions containing them and to their use in the treatment of diseases characterised by elevated - amyloid levels or -amyloid deposits, particularly Alzheimer's disease. |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | Hydroxyethylamine derivatives for the treatment of alzheimer's disease |
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