Hydroxyethylamine derivatives for the treatment of alzheimer's disease

Hydroxyethylamine compounds of formula (I) as defined in the description having Asp2 (-secretase, BACE1 or Memapsin) inhibitory activity, processes for their preparation, to compositions containing them and to their use in the treatment of diseases characterised by elevated - amyloid levels or -amyl...

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Bibliographische Detailangaben
Hauptverfasser:	STANWAY, STEVEN JAMES, VESEY, DAVID R, DEMONT, EMMANUEL H, WALTER, DARYL S, FALLER, ANDREW, REDSHAW, SALLY, MACPHERSON, DAVID TIMOTHY, MILNER, PETER HENRY, NAYLOR, ALAN
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Hydroxyethylamine compounds of formula (I) as defined in the description having Asp2 (-secretase, BACE1 or Memapsin) inhibitory activity, processes for their preparation, to compositions containing them and to their use in the treatment of diseases characterised by elevated - amyloid levels or -amyloid deposits, particularly Alzheimer's disease.