Chk-, Pdk- and Akt-inhibitory pyrimidines, their production and use as pharmaceutical agents

This disclosure relates to pyrimidine derivatives of general formula (I) as inhibitors of kinases, their production as well as their use as medications for treating various diseases, wherein the variables shown in formula (I) are as defined in the specification.

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Bibliographische Detailangaben
Hauptverfasser:	FELDMAN, RICHARD, ARNAIZ, DAMIAN, PHILLIPS, GARY, BRYANT, JUDI, BRIEM, HANS, KUHNKE, JOACHIM, KHIM, SEOCK-KYU, KOCHANNY, MONICA, BOMER, ULF, KOSEMUND, DIRK, ECKLE, EMIL, YUAN, SHENDONG, ESPERLING, PETER, WORTMANN, LARS, BUCKMAN, BRAD, SCHAFER, MARTINA, HUWE, CHRISTOPH
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	This disclosure relates to pyrimidine derivatives of general formula (I) as inhibitors of kinases, their production as well as their use as medications for treating various diseases, wherein the variables shown in formula (I) are as defined in the specification.