Nodulisporic acid derivatives spot-on formulations for combating parasites in mammals and birds

Disclosed herein are spot-on formulations for the treatment or prophylaxis of parasite infestations in mammals or birds which comprise: (1) at least one nodulisporic acid derivative; (2) an acceptable liquid carrier vehicle; and (3) optionally, a crystallization inhibitor. The disclosure also provid...

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Bibliographische Detailangaben
Hauptverfasser:	DE BODE, RONUS, VAN EIJK, PETER JOHANNES SEVAAS SAVIO, BOECKH, ALBERT, SOLL, MARK D
Format:	Patent
Sprache:	eng
Schlagworte:	AGRICULTURE ANIMAL HUSBANDRY BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES, AS HERBICIDES CHEMISTRY FISHING FORESTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HUNTING HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEST REPELLANTS OR ATTRACTANTS PLANT GROWTH REGULATORS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTSTHEREOF TRAPPING
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Beschreibung
Zusammenfassung:	Disclosed herein are spot-on formulations for the treatment or prophylaxis of parasite infestations in mammals or birds which comprise: (1) at least one nodulisporic acid derivative; (2) an acceptable liquid carrier vehicle; and (3) optionally, a crystallization inhibitor. The disclosure also provides for a method of treating parasitic infestations or for the prophylaxis of parasite infestations in non-human mammals or birds which comprise topically applying to said mammal or bird an effective amount of a composition according to the present invention. Further, the disclosure also relates to an amidation process to prepare amide derivatives of nodulisporic acid and to intermediate formed in this process.