Ophthalmological use of roflumilast for the treatment of diseases of the eye

Disclosed is the use of a compound selected from the group consisting of roflumilast, a salt of roflumilast, the N-oxide of the pyridine residue of roflumilast or a salt thereof for the manufacture of a pharmaceutical preparation for the prevention or treatment of a disease of the eye, wherein the d...

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Bibliographische Detailangaben
Hauptverfasser: KOENEN, RUDIGER, LINDER, RUDOLF
Format: Patent
Sprache:eng
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Zusammenfassung:Disclosed is the use of a compound selected from the group consisting of roflumilast, a salt of roflumilast, the N-oxide of the pyridine residue of roflumilast or a salt thereof for the manufacture of a pharmaceutical preparation for the prevention or treatment of a disease of the eye, wherein the disease of the eye is dry eye syndrome (keratitis sicca). An ophthalmological pharmaceutical preparation in the form of eye drops is also disclosed, which comprises a therapeutically effective and pharmacologically suitable amount of an active pharmaceutical ingredient selected from the group of compounds roflumilast, a salt of roflumilast, the N-oxide of roflumilast and a salts thereof together with one or more pharmaceutically acceptable carriers and/or excipients, and which pharmaceutical preparation comprises medium chain length triglycerides.