MS11 gene product encoding for a phosphoglycerate kinase, and a purine nucleoside phosphatase and glucose-6-phosphate isomerase proteins from Group B streprococcus and their use in treating bacterial infection

A peptide encoded by the nucleotide sequence of SEQ ID NO: 3, or a homologue having greater than 70% sequence similarity is described. The peptide sequence can be the amino acid sequence of SEQ ID NO: 4 and can be obtained from Group B streptococcus. The peptide or polynucleotide can be used in a me...

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Hauptverfasser:	HUGHES, MARTIN JOHN GLENTON, MOORE, JOANNE CHRISTINE, FELDMAN, ROBERT, DOBSON, RICHARD JAMES, DOUGAN, GORDON, HENWOOD, CAROLINE JOANNE, EVEREST, PAUL, WILSON, REBECCA KERRY, SANTANGELO, JOSEPH DAVID, LANE, JONATHAN DOUGLAS
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	A peptide encoded by the nucleotide sequence of SEQ ID NO: 3, or a homologue having greater than 70% sequence similarity is described. The peptide sequence can be the amino acid sequence of SEQ ID NO: 4 and can be obtained from Group B streptococcus. The peptide or polynucleotide can be used in a medicament for the treatment of bacterial infections, preferably when the infection is a focal or urinary tract infection. Also described are antibodies and hosts transformed with the peptide.