Detection of immunological memory, T-cell conjugates for pathology imaging and therapy

Described are T-cells specific for an antigen being conjugated to a cytotoxic material, a material capable of being transformed in vivo into a cytotoxic material or causing a pro-form of a cytotoxic material to be transformed in the local vicinity of the T-cell into the cytotoxic material, or a mate...

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Hauptverfasser: ZEUTHEN, JESPER, NIELSEN, STEEN JUEL, GUNDERSEN, HANS JORGEN GOTTLIEB
Format: Patent
Sprache:eng
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Zusammenfassung:Described are T-cells specific for an antigen being conjugated to a cytotoxic material, a material capable of being transformed in vivo into a cytotoxic material or causing a pro-form of a cytotoxic material to be transformed in the local vicinity of the T-cell into the cytotoxic material, or a material capable of enhancing damage caused by applied radiation. The cytotoxic material is preferably an isotope or a radionuclide. (62) Divided out of 521321