Inhibitors of cytosolic phospholipase A2
Disclosed are compounds of formula (I), wherein: R is -(CH2)n-A, -(CH2)n-S-A, or -(CH2)n-O-A, and the remaining substituents are defined herein. Also disclosed are intermediate compounds of formula (A). The compounds of formula (I) are used in the manufacture of medicaments for the treatment of infl...
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creator | BEHNKE, MARK LEO THAKKER, PARESH MCKEW, JOHN CAEDMON CHEN, LIHREN TAM, STEVE YIK-KAI SUM, FUK-WAH CLARK, JAMES DONALD LEE, KATHERINE LIN HU, BAIHUA |
description | Disclosed are compounds of formula (I), wherein: R is -(CH2)n-A, -(CH2)n-S-A, or -(CH2)n-O-A, and the remaining substituents are defined herein. Also disclosed are intermediate compounds of formula (A). The compounds of formula (I) are used in the manufacture of medicaments for the treatment of inflammation, pain, asthma or arthritic and/or rheumatic disorders in a mammal. |
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Also disclosed are intermediate compounds of formula (A). The compounds of formula (I) are used in the manufacture of medicaments for the treatment of inflammation, pain, asthma or arthritic and/or rheumatic disorders in a mammal.</description><edition>7</edition><language>eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2006</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20060331&DB=EPODOC&CC=NZ&NR=533269A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76289</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20060331&DB=EPODOC&CC=NZ&NR=533269A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>BEHNKE, MARK LEO</creatorcontrib><creatorcontrib>THAKKER, PARESH</creatorcontrib><creatorcontrib>MCKEW, JOHN CAEDMON</creatorcontrib><creatorcontrib>CHEN, LIHREN</creatorcontrib><creatorcontrib>TAM, STEVE YIK-KAI</creatorcontrib><creatorcontrib>SUM, FUK-WAH</creatorcontrib><creatorcontrib>CLARK, JAMES DONALD</creatorcontrib><creatorcontrib>LEE, KATHERINE LIN</creatorcontrib><creatorcontrib>HU, BAIHUA</creatorcontrib><title>Inhibitors of cytosolic phospholipase A2</title><description>Disclosed are compounds of formula (I), wherein: R is -(CH2)n-A, -(CH2)n-S-A, or -(CH2)n-O-A, and the remaining substituents are defined herein. Also disclosed are intermediate compounds of formula (A). The compounds of formula (I) are used in the manufacture of medicaments for the treatment of inflammation, pain, asthma or arthritic and/or rheumatic disorders in a mammal.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2006</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZNDwzMvITMosyS8qVshPU0iuLMkvzs_JTFYoyMgvBuKczILE4lQFRyMeBta0xJziVF4ozc0g5-Ya4uyhm1qQH59aXJCYnJqXWhLvF2VqbGxkZuloTFABAPd-J0o</recordid><startdate>20060331</startdate><enddate>20060331</enddate><creator>BEHNKE, MARK LEO</creator><creator>THAKKER, PARESH</creator><creator>MCKEW, JOHN CAEDMON</creator><creator>CHEN, LIHREN</creator><creator>TAM, STEVE YIK-KAI</creator><creator>SUM, FUK-WAH</creator><creator>CLARK, JAMES DONALD</creator><creator>LEE, KATHERINE LIN</creator><creator>HU, BAIHUA</creator><scope>EVB</scope></search><sort><creationdate>20060331</creationdate><title>Inhibitors of cytosolic phospholipase A2</title><author>BEHNKE, MARK LEO ; THAKKER, PARESH ; MCKEW, JOHN CAEDMON ; CHEN, LIHREN ; TAM, STEVE YIK-KAI ; SUM, FUK-WAH ; CLARK, JAMES DONALD ; LEE, KATHERINE LIN ; HU, BAIHUA</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_NZ533269A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2006</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>BEHNKE, MARK LEO</creatorcontrib><creatorcontrib>THAKKER, PARESH</creatorcontrib><creatorcontrib>MCKEW, JOHN CAEDMON</creatorcontrib><creatorcontrib>CHEN, LIHREN</creatorcontrib><creatorcontrib>TAM, STEVE YIK-KAI</creatorcontrib><creatorcontrib>SUM, FUK-WAH</creatorcontrib><creatorcontrib>CLARK, JAMES DONALD</creatorcontrib><creatorcontrib>LEE, KATHERINE LIN</creatorcontrib><creatorcontrib>HU, BAIHUA</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>BEHNKE, MARK LEO</au><au>THAKKER, PARESH</au><au>MCKEW, JOHN CAEDMON</au><au>CHEN, LIHREN</au><au>TAM, STEVE YIK-KAI</au><au>SUM, FUK-WAH</au><au>CLARK, JAMES DONALD</au><au>LEE, KATHERINE LIN</au><au>HU, BAIHUA</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Inhibitors of cytosolic phospholipase A2</title><date>2006-03-31</date><risdate>2006</risdate><abstract>Disclosed are compounds of formula (I), wherein: R is -(CH2)n-A, -(CH2)n-S-A, or -(CH2)n-O-A, and the remaining substituents are defined herein. Also disclosed are intermediate compounds of formula (A). The compounds of formula (I) are used in the manufacture of medicaments for the treatment of inflammation, pain, asthma or arthritic and/or rheumatic disorders in a mammal.</abstract><edition>7</edition><oa>free_for_read</oa></addata></record> |
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title | Inhibitors of cytosolic phospholipase A2 |
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