Prucalopride-N-oxide

Prucalopride-N-oxide

A compound of formula (I), as well as its stereochemically isomeric forms and pharmaceutically acceptable acid addition salts, is disclosed. A process for preparing formula (I) involves the oxidation of a compound of formula (II) with a suitable oxidant in a reaction-inert solvent. The use of the co...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: VAN LAERHOVEN, WILLY JOANNES CAROLUS, SCHUURKES, JOANNES ADRIANUS JACOBUS
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:A compound of formula (I), as well as its stereochemically isomeric forms and pharmaceutically acceptable acid addition salts, is disclosed. A process for preparing formula (I) involves the oxidation of a compound of formula (II) with a suitable oxidant in a reaction-inert solvent. The use of the compound is described to be in the manufacture of a medicament for treating a motility disorder of the intestinal system.