Solid unit dosage forms for oral administration which minimise the impact of coating fractures especially for larger or heavier dosage forms
A pharmaceutical composition in a solid unit dosage form for oral administration in a human or lower animal comprises: a. a safe and effective amount of a therapeutically active agent; b. an inner coating layer selected from the group consisting of poly(methacrylic acid, methyl methacrylate) 1:2, po...
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Zusammenfassung: | A pharmaceutical composition in a solid unit dosage form for oral administration in a human or lower animal comprises: a. a safe and effective amount of a therapeutically active agent; b. an inner coating layer selected from the group consisting of poly(methacrylic acid, methyl methacrylate) 1:2, poly(methacrylic acid, methyl methacrylate) 1:1, and mixtures thereof; c. an outer coating layer which is applied to the inner coating layer. The outer coating layer comprises an enteric polymer that begins to dissolve in an aqueous medium at a pH less than 7. |
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