Substituted 5,6,6a,11b-tetrahydro-7-oxa-5-aza-benzo[c] fluorene-6-carboxylic acid derivatives serving as NMDA antagonists

Substituted 5,6,6a,11b-tetrahydro-7-oxa-5-aza-benzo[c] fluorene-6-carboxylic acid derivatives serving as NMDA antagonists

Described are substituted 5,6,6a,11b-tetrahydro-7-oxa-5-aza-benzo[c]fluorene-6-carboxylic acid derivatives of formula I, methods for the production thereof, medicaments containing these compounds, and to their use for producing medicaments for certain indications, particularly for treating chronic a...

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Bibliographische Detailangaben
Hauptverfasser: JAGUSCH, UTZ-PETER, ENGLBERGER, WERNER GUNTER, PRZEWOSNY, MICHAEL, BLOMS-FUNKE, PETRA, REISSMULLER, ELKE, MAUL,CORINNA, GERLACH, MATTHIAS
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:Described are substituted 5,6,6a,11b-tetrahydro-7-oxa-5-aza-benzo[c]fluorene-6-carboxylic acid derivatives of formula I, methods for the production thereof, medicaments containing these compounds, and to their use for producing medicaments for certain indications, particularly for treating chronic and neuropathic pain with few side effects of nausea, vomiting, dependency, respiratory depression or constipation..