Preparation of flumethasone and its 17-carboxyl androsten analogue

A process for preparing flumethasone (6alpha,9alpha-diffluoro-11beta,17alpha,21-trihydroxy-16alpha-methyl-pregna-1,4-diene-3,20-dione), fulmethasone 21-acetate or its 17-carboxyl androsten analogue is disclosed, wherein the process comprises reacting a compound of formula (IIIa) with an electrophili...

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Hauptverfasser:	VILLAX, IVAN, MENDES, ZITA
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY METALLURGY ORGANIC CHEMISTRY STEROIDS
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creator	VILLAX, IVAN MENDES, ZITA
description	A process for preparing flumethasone (6alpha,9alpha-diffluoro-11beta,17alpha,21-trihydroxy-16alpha-methyl-pregna-1,4-diene-3,20-dione), fulmethasone 21-acetate or its 17-carboxyl androsten analogue is disclosed, wherein the process comprises reacting a compound of formula (IIIa) with an electrophilic fluorination agent.
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subjects	CHEMISTRY METALLURGY ORGANIC CHEMISTRY STEROIDS
title	Preparation of flumethasone and its 17-carboxyl androsten analogue
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