Preparation of flumethasone and its 17-carboxyl androsten analogue
A process for preparing flumethasone (6alpha,9alpha-diffluoro-11beta,17alpha,21-trihydroxy-16alpha-methyl-pregna-1,4-diene-3,20-dione), fulmethasone 21-acetate or its 17-carboxyl androsten analogue is disclosed, wherein the process comprises reacting a compound of formula (IIIa) with an electrophili...
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| Format: | Patent |
| Sprache: | eng |
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| Zusammenfassung: | A process for preparing flumethasone (6alpha,9alpha-diffluoro-11beta,17alpha,21-trihydroxy-16alpha-methyl-pregna-1,4-diene-3,20-dione), fulmethasone 21-acetate or its 17-carboxyl androsten analogue is disclosed, wherein the process comprises reacting a compound of formula (IIIa) with an electrophilic fluorination agent. |
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