Process to prepare oxazolidinones

Process to prepare oxazolidinones

A process for preparing a compound of formula (I) or a salt thereof is disclosed, which comprises reacting a N-aryl-O-alkylcarbamate of formula (II) or a salt thereof, with a compound of formula (III) or a salt thereof, in the presence of a lithium alkaloid base, wherein X and Y are independently H...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: PEARLMAN, BRUCE A, PERRAULT, WILLIAM R, GODREJ, DELARA B
Format: Patent
Sprache:eng
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:A process for preparing a compound of formula (I) or a salt thereof is disclosed, which comprises reacting a N-aryl-O-alkylcarbamate of formula (II) or a salt thereof, with a compound of formula (III) or a salt thereof, in the presence of a lithium alkaloid base, wherein X and Y are independently H or F; W1 is Cl, Br, or -OS(O)2-R; W2 is H or-C(O)-R1; and the other variables are as defined in the specification.