Blood cell production via activation of the hemoglobin scavenger receptor

Disclosed are compositions for stimulating the growth, proliferation, differentiation and/or mobilization of stem and/or progenitor cells. The antibodies disclosed activate the CD163 hemoglobin scavenger receptor signal transduction pathway. This is useful in stimulating hematopoiesis and in treatin...

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Bibliographische Detailangaben
Hauptverfasser:	MUELLER, SUSAN G, BELL, DAVID, MATTHEWS, KATHRYN EMMA
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	Disclosed are compositions for stimulating the growth, proliferation, differentiation and/or mobilization of stem and/or progenitor cells. The antibodies disclosed activate the CD163 hemoglobin scavenger receptor signal transduction pathway. This is useful in stimulating hematopoiesis and in treating a wide range of conditions including cytopenias, anemias and for use in preparing cells for transplantation.