Mercaptoacetylamide derivatives, a process for their preparation and their use

Mercaptoacetylamide derivatives, a process for their preparation and their use

Mercaptoacetylamide derivatives of formula (I) are disclosed. Pharmaceutical compositions incorporating these compounds and processes for preparing said compounds are also disclosed. The compounds possess both angiotensin converting enzyme inhibitory activity and neutral endopeptidase inhibitory act...

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Bibliographische Detailangaben
Hauptverfasser: SEURING, BERNHARD, KLEEMANN, HEINZ-WERNER, LINZ, WOLFGANG, GERKEN, MANFRED, ANDERSON, BARBARA ANN, JABLONKA, BERND, MEHDI, SHUJAATH, FLYNN, GARY A, KOEHL, JACK ROGER
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:Mercaptoacetylamide derivatives of formula (I) are disclosed. Pharmaceutical compositions incorporating these compounds and processes for preparing said compounds are also disclosed. The compounds possess both angiotensin converting enzyme inhibitory activity and neutral endopeptidase inhibitory activity and are useful for the treatment of hypertension and congestive heart failure.