Use as medicine of a compound restoring active principles in vivo

Use as medicine of an active compound of general formula AÆ---VÆ---CÆ (ionic binding) or AÆ_VÆ_CÆ (covalent bonding) capable of restoring at least the entity A by cleaving the corresponding bonds between A' and V', and optionally capable of restoring likewise the entities V and C by cleavi...

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Hauptverfasser: RAPIN, JEAN-ROBERT, HALBITTE, DOMINIQUE
Format: Patent
Sprache:eng
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Zusammenfassung:Use as medicine of an active compound of general formula AÆ---VÆ---CÆ (ionic binding) or AÆ_VÆ_CÆ (covalent bonding) capable of restoring at least the entity A by cleaving the corresponding bonds between A' and V', and optionally capable of restoring likewise the entities V and C by cleaving in vivo the bond V'--- C' or V'_C' provided that: V is a vectorizing biogenic compound, of general formula X-R-Y, wherein R represents a hydrocarbon chain of 2 to 10 carbon atoms, aliphatic, cyclic, or alicyclic, saturated or unsaturated, optionally substituted by C1-C5 alkyl groups, and/or hydroxyl groups; X and Y are each a free acid, amine, or alcohol function. A and C are two respectively different active principles, one of which comprises a chemical function complementary to the function X, capable of reacting with the latter to produce a bond, ionic A'--- V' or covalent AÆ_VÆ, cleavable in vivo, and the other comprises a chemical function complementary to the function Y, capable of reacting with the latter to produce a bond, ionic V'--- C or covalent V'_C', cleavable in vivo.