Stable norastemizole formulations comprising coated norastemizole particles

Disclosed are solid pharmaceutical compositions comprising norastemizole, wherein instability is reduced by the use of particles of norastemizole or pharmaceutically acceptable salts coated with an inert coating to form the composition. Suitable inert coatings include methlcellulose, hydroxymethyl c...

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Hauptverfasser: WALD, STEPHEN A, BUTLER, HAL T, REDMON, MARTIN P
Format: Patent
Sprache:eng
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Zusammenfassung:Disclosed are solid pharmaceutical compositions comprising norastemizole, wherein instability is reduced by the use of particles of norastemizole or pharmaceutically acceptable salts coated with an inert coating to form the composition. Suitable inert coatings include methlcellulose, hydroxymethyl cellulose, carboxymethyl cellulose, hydroxypropylmethylcellulose, hydroxypropyl cellulose, hydroxyethylcellulose, methylhydroxyethylcellulose, sodium carboxymethylcellulose and mixtures thereof. Such compositions are useful in the treatment of allergic disorders, particularly allergic rhinitis. (62) Divided out of 517472