Polynucleotide constructs for increased lysine production

An isolated polynucleotide molecule comprises a nucleic acid molecule encoding an aspartate kinase (ask) polypeptide; (b) a nucleic acid molecule encoding an aspartate-semialdehyde dehyrdogenase (asd) polypeptide; and (c) a nucleic aid molecule encoding a dihydrodipicolinate reductase (dapB) polypep...

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Bibliographische Detailangaben
Hauptverfasser:	TREI, KELLI JEAN, LI, LHING-YEW
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	An isolated polynucleotide molecule comprises a nucleic acid molecule encoding an aspartate kinase (ask) polypeptide; (b) a nucleic acid molecule encoding an aspartate-semialdehyde dehyrdogenase (asd) polypeptide; and (c) a nucleic aid molecule encoding a dihydrodipicolinate reductase (dapB) polypeptide. Also described are vectors, isolated cell and methods of producing lysine by culturing the host cells.