Substituted triazole diamine derivatives as kinase inhibitors

Substituted triazole diamine derivatives as kinase inhibitors

Compounds of formula (I) are disclosed. The compounds are useful in the preparation of a medicament for the treatment or amelioration of kinase mediated disorders. The kinase mediated disorder may be cancer and tumor growth, tumor vascularization, angiopathy, angiogenesis, chemotherapy-induced alope...

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Hauptverfasser: WETTER, STEVEN, EMANUAL, STUART, CONNOLLY, PETER J, GUNINGER, ROBERT, MIDDLETON,STEVE, LIN, RONGHUI, HUANG, SHENLIN
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:Compounds of formula (I) are disclosed. The compounds are useful in the preparation of a medicament for the treatment or amelioration of kinase mediated disorders. The kinase mediated disorder may be cancer and tumor growth, tumor vascularization, angiopathy, angiogenesis, chemotherapy-induced alopecia or restenosis. The medicament containing the disclosed compounds may also be suitable for use as an adjunct to chemotherapy and radiation therapy.